Endothelial cells, found as a single layer lining the luminal surface of blood vessels, play crucial roles in maintaining vascular tone, preventing the formation of intravascular thrombus, and safeguarding against the onset of arteriosclerosis. When endothelial cells are exposed to strong contractile substances, they produce and release factors that exhibit strong vasodilatory effects (NO, prostacyclin, […]
The development of multiple metabolic diseases is heavily influenced by insulin resistance (IR), which not only contributes to increased morbidity and mortality but also results in significant healthcare expenses. In recent years, there has been a growing focus on deep ocean water (DSW) and fucoidan (FPS) due to their promising potential in the medical and […]
Seaweeds contain a multitude of components that have been found to have beneficial effects on the mammalian gut microbiota. These effects include an increase in bacterial diversity and abundance. According to recent studies, diseases like inflammatory bowel disease, immunodeficiency, hypertension, type 2 diabetes, obesity, and cancer are often linked to imbalances in gut bacteria. The […]
Docetaxel, paclitaxel, and cabazitaxel are taxane-based chemotherapies that are commonly used in cancer treatment, but despite their effectiveness, cancer cells tend to develop resistance to these drugs over time, ultimately leading to reduced cancer survival rates and increased chances of recurrence. By inhibiting the function of microtubules, Docetaxel effectively disrupts the process of cell division […]
In this blog post, I will be sharing the study conducted by Guang Yang et al. on “Antitumor activity of fucoidan against diffuse large B cell lymphoma in vitro and in vivo“. The study includes the key findings from their research. B-cell lymphoma, known as DLBCL, is a form of cancer that specifically targets B […]
In the following blog post, I will be focusing on the effects of fucoidan specifically on Oral Squamous Cell Carcinoma (OSCC). The study, “Antitumor Effects of Fucoidan Via Apoptotic and Autophagic Induction on HSC-3 Oral Squamous CellCarcinoma” by Pathanin Chantree et al., revealed that fucoidan can suppress the growth and proliferation of HSC-3 oral squamous […]
The polysaccharides found in seaweed are known for their exceptional potency and diverse composition. In this blog, I would like to introduce the research from a study, “Investigation of effects of fucoidan polysaccharides extracted from two species of Padina on the wound-healing process in the rat” by Moazameh Kordjazj et al. The purpose of this […]
Radiotherapy, along with surgery and chemotherapy, is considered one of the three main pillars that form the foundation of cancer treatment. The prominent characteristics of radiotherapy encompass its lower invasiveness compared to other treatment methods, the option for treatment without resection, and enhanced functionality. It also has excellent shape preservation. Hence, certain individuals can receive […]
A significant majority of cases, ranging from 65% to 95%, experience the development of adhesions after abdominal surgery. Research has shown that adhesive intestinal obstruction may occur in 15% of patients with this condition at a later stage, and it is crucial to mention that surgical intervention is required in nearly one-third of these cases […]
The Hepatitis B virus (HBV) infection is a critical public health problem due to its detrimental effects on the liver, leading to the development of liver cirrhosis and hepatocellular carcinoma. If hepatitis persists, it may progress to chronic hepatitis, cirrhosis, and even liver cancer (hepatocellular carcinoma). A vaccine for hepatitis B is available, yet it […]