The subject of this blog is the study by Yan Xu et al., “Fucoidan Improves D-Galactose-Induced Cognitive Dysfunction by Promoting Mitochondrial Biogenesis and Maintaining Gut Microbiome Homeostasis.” The study aimed to explore the protective impact of fucoidan from Saccharina japonica in D-galactose-induced cognitive impairment and its mechanism. Fucoidan, a natural substance that shows potential, is […]
Author: Molly
Degree of Doctor of Naturopathy
Hypertension affects inflammatory pathological changes in the retina. In this blog, the study, “Fucoidan modulates SIRT1 and NLRP3 to alleviate hypertensive retinopathy: in vivo and in vitro insights” by Jing Li et al, that investigate whether sirtuin 1 (SIRT1) controls angiotensin II (Ang II)-induced hypertensive retinopathy and inflammation by regulating the activation of NOD-like receptor […]
Mitochondrial dysfunction is thought to play a key role in dopamine neuron degeneration in patients with sporadic and familial Parkinson’s disease (PD), so approaches aimed at preserving mitochondrial function may hold great promise in the prevention and treatment of PD. In this blog, it presents the study, “Fucoidan Protects Dopaminergic Neurons by Enhancing the Mitochondrial […]
The marine-derived polysaccharide fucoidan combines multiple biological activities. Various in vitro and in vivo studies have demonstrated that fucoidan exhibits antiviral, antitumor, antioxidant, anti-inflammatory, and anticoagulant properties. In this blog, I would like to share the study, “Crude Fucoidan Extracts Impair Angiogenesis in Models Relevant for Bone Regeneration and Osteosarcoma via Reduction of VEGF and […]
In the United States, thyroid cancer accounts for approximately 2% of malignant tumors and is responsible for more than 1,600 cancer-related deaths annually. Thyroid cancer accounts for 1% of human cancer cases and includes well-differentiated thyroid cancer of the papillary and follicular types, which account for more than 95% of thyroid cancer cases, and anaplastic […]
Fucoidans, laminarin, and alginate are rich sources of compounds that may have beneficial effects on the mammalian gut microbiota by increasing bacterial diversity and abundance. Gut bacterial imbalances have been linked to the development of diseases such as inflammatory bowel disease, immune deficiency, hypertension, type 2 diabetes, obesity, and cancer. Polysaccharides act as prebiotics to […]
Mitochondria are the most commonly damaged organelles in dopaminergic neurons in Parkinson’s disease (PD) patients. Despite the importance of protecting neuronal mitochondria in PD patients, the detailed mechanisms of mitochondrial dysfunction in the development and pathophysiological progression of PD remain to be elucidated. So, in this blog, I would like to inform of the study, […]
Nephrotic syndrome (NS) is a clinical syndrome with various causes that are caused by excessive excretion of protein, typically resulting in the accumulation of fluid in the body (edema), along with decreased blood levels of a protein called albumin and increased blood levels of lipids. It is primarily characterized by severe proteinuria, hypoalbuminemia, and edema. […]
Pulmonary fibrosis is a chronic, progressive, and fatal interstitial lung disease, but there is currently no effective treatment that can improve the prognosis of patients. In this blog, I would like to introduce the research results “Isolation, Characterization, and Anti-Idiopathic Pulmonary Fibrosis Activity of a Fucoidan from Costaria crostata” by Sijie Wei et al, which […]
Fucoidan (Fucus vesiculosus), a natural sulfated polysaccharide found in various brown algae, is well known to mediate anti-cancer effects through cell cycle arrest and induction of apoptosis, but the role of the tumor suppressor p53 in the mechanism of action of fucoidan remains unclear. In this blog, I would like to introduce the research,” Induction […]